Secured Collaborative AI for Oncology Research

at Dana Farber

Clinical Oncology Research Labs are at the forefront of cancer care and classification research, continually advancing the field through innovative studies and clinical trials. Faced with the challenge of analyzing vast oncology data spread across multiple institutions, these labs require a solution that allows AI model training and deep learning on large, decentralized datasets without compromising the security of sensitive clinical data.

The problem

Challenges in Collaborative Research

Accessing and utilizing large-scale oncology data from multiple medical centers introduces significant privacy and security challenges. Pathology images, and other Protected Health Information (PHI), cannot be freely shared among organizations, necessitating a secure method of collaborative analysis. Today, data regulations are largely addressed by manual checkpoints that satisfy compliance, but at great cost to time and data quality. This is particularly important in fields like breast cancer, lung cancer, prostate cancer, and colorectal cancer research, where such sensitive data is essential for cancer diagnosis and treatment decisions.

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The Solution

Medical Center Data Remains Secure

Duality Technologies has developed a secure collaboration platform utilizing federated learning and a trusted execution environment that adheres to the stringent security and privacy standards required in a clinical setting. This framework maintains a structure where each clinical practice and medical center’s data stays securely on-site. The AI model training occurs locally, and only the model weights are transmitted. These weights are aggregated on a global server, and to ensure maximum security, Duality employs a trusted execution environment. This guarantees that the weights are encrypted during transmission and remain inaccessible to unauthorized parties.
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Benefits

“Ongoing precision medicine studies can immediately benefit from these capabilities by enabling secure collaboration across clinical institutions without requiring complex data sharing agreements or compromising individual-level privacy. This technology can also empower patients to participate in research studies directly and receive personalized results knowing that their individual data will not be exposed.”

Dr. Alexander Gusev

Secure Federated Learning for Oncology Research

How we do it

The secure federated learning study conducted by the Dana Farber Cancer Institute in collaboration with Duality Technologies highlights significant operational benefits for cancer research. This approach has proven pivotal for multi-institutional collaborative oncology research, offering agility, flexibility, and privacy protection for sensitive data for all participants.

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